Monday, 10 July 2017

Averaged and Personalized Mathematical Modeling of Biomechanics of a System Limb-Orthosis

Despite the growing use of orthoses in clinic, sports and everyday life, and availability of a number of medical guides and atlases for orthoses the line of activity, involvingmechanical and mathematical modeling of "Leg-Orthosis" system, is as yet only at the beginning of its development.

Orthosis
Publications relating to modeling limbs orthotics per se (biomechanics of foot and insoles constitutes actually a separate independent area of research) by methods of solid mechanics, are isolated yet, and they relate only to orthosis itself and completely ignore the very limb and its mechanical properties. At the same time such studies are needed to resolve a number of important issues. For example, it is known that the rate of tissue regeneration depends on the loading level and program. It is therefore important to find out whether it is possible to control the limb unloading in an orthosis – for example, through a change in the orthosis lateral compression, etc. Read more>>>>>>>

Thursday, 6 July 2017

Effect of (He-Ne) Laser on Etching Parameters of CR-39 Irradiated with Alpha Particles

Alpha Particles
The effect (He-Ne) laser on the registration properties of alpha particle tracks on CR-39 track detector was studied. CR-39 detectors were exposed to different powers (1, 5 and 10 mW) of He-Ne laser beam at different times (5, 10 and 15 min) and then irradiated to alpha-particles from 226Ra source (laser+α). Track diameters (D), track density

(ρ)    were determined using 6.25 N NaOH at 60°C.
Bulk etching rate (VB), track etching rate (VT), critical angle (Өc), etching efficiency (η), Sensitivity (S), etching ratio rate (V) were calculated.

It’s found increase in the values of (D, ρ, VB, VT and Өc) with increase in the exposure times of laser at each power case, and decrease in the values of (η, S and V) with increase in the exposure time of laser at 1 mw power, while increasing within increase of exposed times of laser at (5 and 10 mW).

The optimum etching time of CR-39 detectors was (4 h) with NaOH etchant solation and 6.25 at temperature 60oC.

Wednesday, 5 July 2017

Sporotrichosis: An Infectious Emerging Mycosis of Zoonotic Potential

Sporotrichosis (Berumann`s disease, peat moss disease, rose gardener’s disease, Schenck`s disease) is an infectious, subcutaneous or chronic granulomatous mycotic disease of humans aswell as animals. It is a life- threatening disease in immune compromised patients.

Sporotrichosis
Sporotrichosis is considered as an emerging zoonotic fungal disease in many regions of the world. An American researcher Benjamin Schenck is credited to identify the organism for the first time in 1898. The presence of asteroid bodies in pus from cutaneous lesions was first time noticed by Slendore in 1908. In 1920, Ghosh described the first case of sporotrichosis from Kolkata, which established the endemic focus of infection in the North-eastern belt of India. The disease is endemic in many regions of the world including India. Sporotrichosis is a disease of occupational risk, affecting agricultural workers, farmers, gardeners, and mine workers.Read more>>>>>

Monday, 3 July 2017

Green Synthesis of Silver Nanoparticles from Punica granatum L. and Its Antimicrobial Activity

Silver Nanoparticles
Green synthesis of nanoparticles was done from Punica granatum L. by using Silver nitrate (AgNO3) from the exocarp, mesocarp and the juice of Aarakta, a local variety of Maharashtra, India.

In this work, we have explored an inventive contribution for synthesis of silver nanoparticles using the peel (exocarp and mesocarp) and the seed juice of pomegranates. The procedures for development of stable silver nanoparticles were characterized.

The synthesis of nanoparticles was confirmed through UV-Visible spectroscopy. The interaction between nanoparticles with functional groups was confirmed by using FT-IR and PCA was performed. The antimicrobial activity of these pomegranate synthesized silver nanoparticles was evaluated against different microorganisms viz. Escherichia coli, Pseudomonas aeruginosa and Proteus vulgaris.

Friday, 30 June 2017

Laterality and Gender in Congenital Upper Limb Deficiencies

Laterality and gender in congenital upper limb deficiencies have been an area of debate in prosthetics for many years. Images such as the ‘Limbless children, Moscow’ in 1993 by GerdLudwig in the National Geographic showed a line of 8 children, all with left sided congenital upper limb deficiency.

Upper Limb Deficiencies
The line consisted of 6 girls and two boys. Did this picture depict what has been considered by the experts to be true when it comes to congenital upper limb deficiencies – It is more common on the left side and more common in females? A bias towards more left upper limb congenital absences has been commented on in a number of papers in the late 90’s. There appeared to be no conclusive explanation for this preponderance. A paper by Corballis and Morgan in 1979 suggested that the developing embryo is under the influence of a left-right maturational gradient which seems to favour earlier or more rapid development on the left than the right.



Monday, 26 June 2017

Hadronic Radiation of Biological Molecules

As hadronic radiation therapy becomes an ever more important treatment method for various forms ofcarcinogenesis, it becomes ever more important to understand the interaction of fast, heavy, ions, such as protons or alpha particles, with biologically significant molecules.

Biological Molecules
In general, this implies understanding of the transfer of the kinetic energy of the incoming ion to electronic energy of the target molecule, which can subsequently lead to fragmentation, and thus loss of function, of the carcinogen target. The use of hadronic radiation projectiles instead of X-rays has a large advantage in modern times, as the energy deposited by hadronic projectiles is much more localized than that from X-rays. Thus, energy from the radiation can be much more accurately focused on the carcinogenic area.



Friday, 23 June 2017

Usage of Pedorthics in Managing Diabetic Foot

Diabetes is no more the developed countries disease, it has spread its roots equally in the developing country, like in India. Diabetes and its complications are now rapidly becomingthe second threat to human longevity.

Diabetic Foot

There are different types of diabetes, but the common affected areas in all cases start with the foot. The insensate foot leads to the largest trend of amputation. Abnormal pressure on the insensate foot plays an important role in the pathogenesis of diabetic foot ulcers. Failure to relieve pressure is the main cause of non-healing diabetic ulcers. Generally, people on a common note feel that wearing footwear prevents and cures diabetes. But different studies have shown that about 83% of diabetic subjects did not wear appropriate footwear. The common foot disorders start with the collapse of the normal foot arch or generally referred to as the flat foot type.